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AOD-9604 is a modified peptide fragment derived from the C-terminal region of human growth hormone (HGH), specifically amino acids 176-191. It was originally developed by researchers at Monash University in Australia as part of investigations into the metabolic signaling pathways associated with human growth hormone.
Unlike full-length growth hormone, AOD-9604 represents only a small fragment of the HGH molecule and is studied primarily for its role in lipid metabolism signaling pathways without interacting directly with growth-related hormone receptors. Because of this selective activity, the peptide has attracted interest in metabolic and cellular research.
Researchers continue to study AOD-9604 in laboratory environments to better understand how HGH fragments influence fat metabolism, cellular differentiation, and tissue signaling mechanisms.
AOD-9604 has been examined in multiple experimental models related to metabolic regulation and cellular biology.
Laboratory studies suggest that the HGH 176-191 fragment may interact with signaling pathways involved in lipid metabolism.
Research models have explored how this peptide fragment may influence mechanisms related to:
lipolytic signaling pathways
lipid storage regulation
adipose tissue metabolic activity
These investigations focus on understanding the biological role of HGH fragments in metabolic communication within adipose tissue.
Experimental research has also explored how AOD-9604 may interact with cell differentiation pathways.
In vitro studies suggest the peptide may influence processes involved in:
myoblast differentiation into muscle cell models
mesenchymal stem cell differentiation pathways
cellular growth signaling in skeletal tissues
These findings have led researchers to explore broader questions about the biological roles of HGH fragments in tissue signaling.
AOD-9604 has also been examined in experimental studies involving bone and cartilage cell cultures.
Preclinical models have investigated whether the peptide may influence cellular pathways associated with:
chondrocyte activity
collagen and proteoglycan synthesis
osteogenic signaling processes
These research directions aim to understand how peptide fragments may interact with musculoskeletal cellular systems.
Researchers have investigated the peptide’s potential influence on cellular repair and regeneration mechanisms.
Experimental models have explored how AOD-9604 may interact with cellular pathways involved in:
cartilage regeneration signaling
extracellular matrix production
stem cell differentiation processes
These studies continue to expand scientific understanding of how peptide fragments derived from growth hormone may influence tissue biology.
Compound: AOD-9604 (HGH Fragment 176-191)
Form: Lyophilized peptide powder
Grade: Research grade
Storage: Refrigerate at 2-8°C prior to reconstitution
Use: Laboratory research only
Peptides are short chains of amino acids that act as signaling molecules within the body. They are involved in a wide range of biological processes, including tissue repair, immune response, and cellular communication.
In research settings, peptides are studied for their ability to interact with specific receptors and pathways, making them valuable tools for scientific and laboratory analysis.
All peptides sold by Polar Peptides are intended strictly for research and laboratory use only and are not approved for human consumption.
All peptides are supplied in lyophilized (freeze-dried) form to ensure long-term stability during storage and shipping.
Unreconstituted vials should be stored in a cool, dry place away from direct light. For extended storage, refrigeration is recommended.
Once reconstituted for research purposes, peptides should be kept refrigerated and handled using sterile laboratory practices to maintain integrity.
Proper storage and handling are essential to preserve peptide stability, purity, and accuracy in research applications.
All orders are shipped directly from our Canadian fulfillment centre within 24 hours (Monday–Friday), ensuring fast and reliable shipping for all peptide products.
Delivery typically takes 2–5 business days depending on your location and the shipping method selected at checkout. We partner with trusted carriers to ensure secure and temperature-stable transit where required.
Once your order ships, a confirmation email with a real-time tracking number will be sent so you can monitor your package every step of the way.
We are committed to providing fast delivery across Canada, making Polar Peptides one of the most reliable peptide suppliers in the country.
We currently accept secure payments via Interac e-Transfer, the safest and fastest method for Canadian customers purchasing research peptides.
After placing your order, you will automatically receive an email with clear and detailed payment instructions. This ensures accurate payment processing and helps us ship your order without delay.
Your order will be prepared and shipped as soon as payment is successfully received and confirmed by our system.
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Each vial contains peptides at approximately 104% of the labeled amount, providing full accuracy and consistency for research applications.
All vials arrive as lyophilized (freeze-dried) powder requiring reconstitution with bacteriostatic water . This is necessary because once reconstituted with liquid, they must be refrigerated to maintain stability. We do not ship reconstituted peptides.
Vial dimensions are standardized at 16mm diameter and 38mm height, with a maximum fill capacity of 3ml. This ensures compatibility with common research-use storage and reconstitution tools.
Our packaging and vial quality meet high industry standards, offering consistent quality across all peptide batches.
All peptides offered by Polar Peptides undergo strict quality-control procedures, including independent third-party analytical testing for purity, identity, and consistency.
We use advanced testing methods such as HPLC (High-Performance Liquid Chromatography) and Mass Spectrometry to verify that each peptide meets the required research-grade standards.
Every batch is tested before being released, and full Certificates of Analysis (COAs) can be provided upon request. This includes data on purity percentage, molecular confirmation, and batch identification.
For the most up-to-date COAs and lab documentation, simply email us and our team will send the current testing reports for the specific peptide(s) you are interested in.
We are committed to transparency, accuracy, and reliability—ensuring that researchers across Canada receive high-quality, fully verified peptide products every time.
Note: Due to factors such as U.S. cross-border shipping delays, laboratory backlog, and the fact that we offer over 40 different products, it is not always possible to have up-to-date or readily available COAs for every batch. We always strive to provide them when possible, but please understand that COAs may not always be available immediately.
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